BORON-CONTAINING PROTEASOME INHIBITOR USED AFTER PRIMARY CANCER THERAPY

user-5d7f3c40530c708f991f6404(2019)

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摘要
To provide a method or a dose regimen containing a proteasome inhibitor of the formula (I) for treating cancer or inhibiting relapse or progress of cancer, or a pharmaceutically acceptable salt thereof, wherein a ring A, Z, and Zare defined in the application.SOLUTION: Multiple myeloma which is B cell tumor of malignant cells in bone marrow is still incurable although a new therapy is progressing by a proteasome inhibitor (PI), an immunomodulator (IMiD) and a stem cell transplantation (SCT) therapy.SELECTED DRAWING: None
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关键词
Proteasome inhibitor,Multiple myeloma,Cancer,Bone marrow,Transplantation,Stem cell,B cell,Regimen,Cancer research,Medicine
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