Single Oral Beta-Cryptoxanthin Administration Increases Its Serum Concentration And Enhances Peripheral Blood Neutrophil Function In Holstein Cattle

We investigated the effect of oral administration of beta-cryptoxanthin (beta-CRX) on its serum concentration and peripheral neutrophil functions by the chemiluminescence (CL) response in Holstein cattle. A single oral administration of beta-CRX was performed for serum beta-CRX concentration (0, 0.05, 0.1, or 0.2 mg/kg body weight [BW]) and for peak CL response of peripheral neutrophils (0.2 mg/kg BW). The serum beta-CRX concentration was peaked on 2 days after, similar to peak CL response on 3 days after beta-CRX administration. Therefore, a single oral administration of beta-CRX (0.2 mg/kg BW) induces higher serum concentration and concurrently enhances bactericidal ability of peripheral neutrophils in Holstein cattle.