Identification and characterization of a new 34 kDa MORN motif-containing sporozoite surface-exposed protein, Cp-P34, unique to Cryptosporidium

•A novel Cryptosporidium sporozoite surface antigen, Cp-P34, was discovered.•Cp-P34 is the target of a camelid VHH antibody selected on fixed sporozoites.•Non-permeabilized sporozoites are brightly stained by antibodies to Cp-P34.•Cp-P34 deposits in sporozoite gliding trails, similarly to known virulence factors.•Cp-P34 is a MORN-containing protein, apparently unique to Cryptosporidium spp.