The Advance of Plasmonic-Electric Nanopipette Sensing in Single Cells

Nanopipette provides a promising limited space, which demonstrates achievements in optical, electrochemical, and mass spectral measurements on the nanoscales. It has been applied to uncover the potential properties of populations and dynamics of individual molecules and individual particles. Plasmonic-electric nanopipette tip probe of individual cells provides more accurate diacrisis and grasp of elementary chemical and biological processes. Recent advances in individual cells provide tools for hypersensitive analysis. In this review, we summarize the results of recent progresses in studying nanopipette photonic and electrical probe tips of individual cells. The benefits of confining these optical-electric nanopipette tip probe to a compatible dimension measurement interface are instantiated. Ultimately, the opportunities and challenges of optical-electric nanopipette tip probe of single cell are addressed.