In silico strategic curation, retrieval and prediction of novel antimicrobial peptide from Locusta migratoria transcriptome

Joon Ha Lee,Hoyong Chung,Yong Pyo Shin,In-Woo Kim,Sathishkumar Natarajan,Karpagam Veerappan,Minchul Seo,Junhyung Park,Jae Sam Hwang

Journal of Asia-Pacific Entomology（2021）

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摘要

•Immunized Locusta migratoria transcriptome was de novo assembled.•Decoded Locusta migratoria antimicrobial peptide from its transcriptome.•Curated antimicrobial peptides pass molecular and aggregation filters.•Two synthesized Locusta migratoria peptides showed antimicrobial activity.

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关键词

Locusta migratoria,Antimicrobial peptide,Transcriptome,De novo assembly, Hemolysis

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