RiPPMiner-Genome: A Web Resource for Automated Prediction of Crosslinked Chemical Structures of RiPPs by Genome Mining

Priyesh Agrawal, Sana Amir, Deepak,Drishtee Barua,Debasisa Mohanty

Journal of Molecular Biology（2021）

引用 16|浏览6

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摘要

•Completely automated prediction of crosslinked chemical structure of RiPPs using genomic sequences of RiPP BGCs.•ML approach for identifying precursor from multiple small ORFs in a RiPP BGC & predicting cleavage and cross-links.•Identification of uncrosslinked modified residues in lanthipeptides and enhancement of prediction accuracy.

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关键词

RiPP,cross-link,genome mining,machine learning,chemical structure prediction

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