Clinical Impact of Stump Closure Reinforced With Hemopatch on the Prevention of Clinically Relevant Pancreatic Fistula After Distal Pancreatectomy: A Multicenter Randomized Trial

Selman Uranues,Abraham Fingerhut,Orlin Belyaev,Alessandro Zerbi,Ugo Boggi, Matthias W. Hoffmann,Daniel Reim,Alessandro Esposito,Florian Primavesi,Peter Kornprat,Roberto Coppola, Georgio P. Fragulidis,Mario Serradilla-Martin,Orhan Alimoglu,Andrea Peri,Bogdan Diaconescu

Annals of Surgery（2021）

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摘要

The results of the first randomized trial evaluating Hemopatch-reinforced pancreatic stump after DP to prevent type B/C POPF do not allow us to conclude that the risk of B/C POPF was lower. Based on the NNT, however, routine use of Hemopatch after DP may result in fewer complications (including POPF) overall, especially in cases with hand-sewn closure of the pancreatic stump or main pancreatic duct.

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