Select Atrophied Regions in Alzheimer disease (SARA): An Improved Volumetric Model for Identifying Alzheimer Disease Dementia

•Volumetric MRI classification models can detect symptomatic Alzheimer disease.•Detection improved by using multiple regions instead of hippocampal volume alone.•Detection not improved by including age or controlling for age-related atrophy.•Most useful when frontotemporal dementia or non-neurodegenerative diseases possible.