Genome-Scale and Systematic Variant Profiling Delineates the Radiogenomic Landscape of Cancer
Radiotherapy and Oncology(2021)
摘要
We report on a large-scale profiling effort to identify mutant alleles that govern radiation survival. Our results reveal new insights into potentially actionable determinants of tumor sensitivity to radiotherapy and accelerate clinical validation of common and rare gene mutations that impact radiation sensitivity.
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