Rethinking prognostic factors in locally advanced or metastatic urothelial carcinoma in the immune checkpoint blockade era: a multicenter retrospective study

J Ruiz-Bañobre, A Molina-Díaz, O Fernández-Calvo, N Fernández-Núñez, A Medina-Colmenero, L Santomé,M Lázaro-Quintela, M Mateos-González, N García-Cid,R López-López,S Vázquez, U Anido-Herranz

ESMO Open（2021）

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摘要

•Monotherapy with anti-PD-(L)1 antibodies is a safe and effective treatment option in mUC.•Peritoneal metastases represent an independent prognostic factor in mUC.•The use of PPI correlates with poor therapeutic outcomes.•A new three risk category prognostic model enables OS prediction.

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关键词

immunotherapy,peritoneum,prognosis,proton-pump inhibitors,real world,urothelial carcinoma

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