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Advanced NSCLC Patients with EGFR T790M Harboring TP53 R273C or KRAS G12V Cannot Benefit from Osimertinib Based on a Clinical Multicentre Study by Tissue and Liquid Biopsy

Yulong Fu,Anqi Wang,Jieqi Zhou,Wei Feng,Minhua Shi,Xiao Xu,Hongqing Zhao,Liming Cai,Jian Feng,Xuedong Lv,Xiaodong Zhang,Wenjing Xu,Zhengrong Zhang,Guoer Ma,Jian Wang,Tong Zhou,Dahai Zhao,Haohui Fang,Zeyi Liu,Jian-an Huang

Frontiers in Oncology（2021）

Cited 16|Views28
Key words
non-small cell lung cancer,liquid biopsy,gene sequencing,epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI),drug resistance
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