Chiral Discrimination Tyrosine Enantiomers Based On N-Acetyl-L-Cysteine Modified Znfe2o4@Sio2 Nanoparticles

N-acetyl-L-cysteine (NALC) functionalized ZnFe2O4@SiO2 (ZnFe2O4@SiO2-NALC) was synthesized and exhibited simplicity, rapidity and high selectivity in the separation of chiral tyrosine (Tyr) enantiomers. The chiral nanocomposite of ZnFe2O4@SiO2-NALC was characterized by X-ray powder diffraction (XRD), infrared spectroscopy (FT-IR), energy dispersive X-ray spectroscopy (EDS), scanning electron microscopy (SEM), high resolution transmission electron microscopy (HRTEM) and vibrating sample magnetometer (VSM). This is the first synthesis of ZnFe2O4@SiO2-NALC for chiral recognition. The proposed optical spectroscopic techniques (UV -Vis spectrum and fluorescence spectra) showed excellent enantiospecificity for Tyr enantiomers. Furthermore, the experimental parameters such as the Tyr concentration and the pH values were optimized.