细胞因子诱导的杀伤细胞在感染性疾病免疫治疗中的作用
Chinese Journal of Clinical Laboratory Science（2013）
Abstract
细胞因子诱导的杀伤细胞(cytokine-induced killer cells,CIK细胞)是体外采用多种细胞因子扩增的异质性细胞群,具有增殖活性高、杀瘤活性高、非MHC限制性、安全性高等特点.此外,CIK细胞治疗可明显改善肿瘤患者免疫抑制状态,提高机体的免疫功能.CIK细胞在乙型肝炎、丙型肝炎、EB病毒相关的移植后淋巴组织增生性疾病等非肿瘤性疾病中也有应用研究的相关报道.CIK细胞过继免疫治疗有助于提高机体免疫功能,可有效抑制肝炎病毒复制、降低肝炎病毒载量、减轻肝脏炎症.本文就CIK细胞在感染相关性疾病治疗中的应用作一综述.
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