表现为混杂密度磨玻璃结节的肺原位腺癌和微浸润腺癌的HRCT影像学表现
Modern Practical Medicine（2019）
Abstract
目的 探讨表现为孤立性肺混杂密度磨玻璃结节的原位腺癌(AIS)和微浸润腺癌(MIA)的高分辨率CT影像学差异.方法 收集199例经最终病理证实的孤立性肺混杂密度磨玻璃结节患者,包括89例AIS患者(AIS组)和110例MIA患者(MIA组),采用单因素和多因素分析比较AIS和MIA的HRCT影像学特征.结果 两组mGGN在分叶征、毛刺征、胸膜牵拉征、空气支气管征、结节CT值、实性成分CT值、实性成分直径及结节直径差异均有统计学意义(均P＜ 0.05).MIA组mGGN有更多的空气支气管征(P=0.049),更高的结节CT值(P=0.001).空气支气管征的AUC为0.784,结节CT值鉴别AIS组mGGN和MIA组mGGN的截止值为-540HU,敏感性95.51％,特异性100.00％,AUC为0.992.结论 HRCT影像学特征能准确地鉴别表现为孤立性肺混杂密度磨玻璃结节的AIS和MIA,并能为临床医生提供帮助.
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