Metabolite profiling of chondrosarcoma cells: A robust GC-MS method for the analysis of endogenous metabolome

Jinfeng Zhu,Mengmeng Zhang,Jinxiu Guo, Xueke Wu,Shaomin Wang,Yubing Zhou,Hongmin Liu

Journal of Chromatography B（2021）

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摘要

•First metabolic profiling of chondrosarcoma SW-1353 cells.•Optimized pretreatment protocols for chondrosarcoma cell metabolite profiling.•Representative metabolites were quantitatively determined.•Simple, robust, and reproducible GC–MS method.•Helpful to further pathophysiology research of chondrosarcoma by metabolomics.

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关键词

Chondrosarcoma cells,Metabolomics,Sample pretreatment,Gas chromatograph-mass spectrometry

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