Comparison Of Non-Operative Mesotherapy And Surgery In The Management Of Superficial Lipomas

Background: Lipomas are benign adipocytic tumours. Surgical excision is the gold standard for treating such lipomas, but it results in unaesthetic scarring.Methods: A total of 126 patients were randomised into two groups. The patients i n Group A underwent mesotherapy (n = 66) and those in Group B underwent surgery (n = 60). The patients in Group A group received six sessions of mesotherapy treatment at 2-week intervals. Both groups were followed up for 12 weeks, during which they were assessed for complications arising from treatment, reduction of the size of the lipoma and cosmetic outcomes.Results: The overall mean age of the patients was 32.93 (+/- 10.1) years old and the mean volume of the lipomas was 2.29 (+/- 3.8) mL. A 55.86% (P = 0.0032) mean reduction in the volume of lipomas was noted in the patients who received mesotherapy, while one patient showed a gain of 16% by volume. The patients in Group A (cosmetic score >= 4: 63%) were happier with the treatment than those in Group B (cosmetic score >= 4: 21%).Conclusion: Our findings indicate that mesotherapy modestly reduces the volume of lipomas with very few and minor complications and excellent cosmetic outcomes.