Development of an UHPLC-diode arrays detector (DAD) method for the analysis of polydatin in human plasma

S Montanari,L Davani, V Tumiatti, M Dimilta,A V Gaddi,A De Simone,V Andrisano

Journal of Pharmaceutical and Biomedical Analysis（2021）

引用 7|浏览4

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摘要

•Development and validation of UHPLC analytical method for the characterization of polydatin bioavailability.•Average recovery higher than 98 %.•Sensitivity in the nanomolar range.•Fast detection and separation of polydatin and resveratrol in human plasma and urine.•Application of the method for pharmacokinetic characterization of dietary supplements in human.

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关键词

Polydatin,Resveratrol,Ultra High Performance Liquid Chromatographic analysis,Human plasma,Pharmacokinetics

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