Nuclear Periphery and Telomere Maintenance: TERRA Joins the Stage.
Trends in genetics : TIG(2021)
摘要
Long noncoding (lnc)RNAs derived from telomeres, the ends of linear eukaryotic chromosomes, help to maintain telomere length and stability by multiple means, including regulation of telomerase activity and recombination-based telomere maintenance. New findings in yeast promote a model in which telomere attachment to the nuclear envelope regulates telomere transcription and maintenance.
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