Human primary bone giant-cell tumor cell line GCTB28-luc and construction method and application thereof

The invention provides a human primary bone giant-cell tumor cell line GCTB28-luc and a construction method and application thereof. The human primary bone giant-cell tumor cell line GCTB28 is preserved in the China center for type culture collection, the address is the Wuhan university in Wuhan city in China, and the preservation number is CCTCCNO: C2018178. The constructed cell line GCTB28-luc has the characteristics of human primary bone giant-cell tumor cells, meets the line establishment criteria, can be cultured in vitro in a culture medium, can grow steadily in vitro and achieve continuous passage, can be used for building a mechanism model of bone giant-cell tumor, can serve as a cell material used for bone giant-cell tumor pathogenesis and individualized treatment in vitro research, and can be used for preparing, screening, and evaluating drugs resisting bone giant-cell tumor.