Phenyl 1,2-isoxazole or phenyl 1,2-pyrazole compounds and application thereof

user-5f8cf7e04c775ec6fa691c92(2014)

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摘要
The invention discloses application of phenyl 1,2-isoxazole or phenyl 1,2-pyrazole compounds with the structure shown in the specification. Biological activity tests prove that the compounds have obvious activity of inhibiting heat shock protein 90. Therefore, the phenyl 1,2-isoxazole or phenyl 1,2-pyrazole compounds provided by the invention can be used as inhibitors of heat shock protein 90 for treating cancers.
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关键词
Isoxazole,Pyrazole,Heat shock protein,Biological activity,Combinatorial chemistry,Chemistry
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