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Novel (R)-6,6A,7,8,9,10-hexahydro-5h-pyrazino[1,2-a][1,n]naphthyridines As Potent and Selective Agonists of the 5-HT2C Receptor.

Thomas O. Schrader,Xiuwen Zhu,Michelle Kasem,Albert Ren,Chunyan Liu,Chunrui Wu,Huong Dang,Minh Le,Joel Gatlin,Kelli Chase,John Frazer,Kevin T. Whelan,Andrew J. Grottick,Clayton Hutton,Jeremy Barden,Chuan Chen,Alvaro Ortiz,Konrad Feichtinger,Graeme Semple

Bioorganic & Medicinal Chemistry Letters（2021）

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关键词
5-HT2C agonists,Lorcaserin,Naphthyridine,CNS drugs,Tricyclic amines
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