Low vitamin D, but not tobacco use or high BMI, is associated with long-term disability progression in multiple sclerosis

Kristin Wesnes,Kjell-Morten Myhr,Trond Riise,Silje Stokke Kvistad,Øivind Torkildsen,Stig Wergeland,Trygve Holmøy,Rune Midgard,Alla Bru,Astrid Edland,Randi Eikeland,Sonia Gosal,Hanne F Harbo,Grethe Kleveland,Yvonne S Sørenes,Nina Øksendal,Kjetil Bjørnevik

Multiple Sclerosis and Related Disorders（2021）

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摘要

•Vitamin D, tobacco use, and BMI may influence long-term prognosis in MS•We found a significant association for vitamin D and 10-year disability progression•The association was mainly driven by seasonal low vitamin D levels during spring•Tobacco use and BMI had less importance for disability progression in our study

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关键词

Multiple Sclerosis,Lifestyle factors,Vitamin D,Tobacco,Body Mass Index,Disability progression

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