Reassortant Cache Valley Virus Associated With Acute Febrile, Nonneurologic Illness, Missouri

Molly Baker,Holly R Hughes,S Hasan Naqvi, Karen Yates,Jason O Velez, Sophia McGuirk, Barb Schroder,Amy J Lambert,Olga I Kosoy, Howard Pue,George Turabelidze,J Erin Staples

CLINICAL INFECTIOUS DISEASES（2021）

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摘要

An adult male from Missouri sought care for fever, fatigue, and gastrointestinal symptoms. He had leukopenia and thrombocytopenia and was treated for a presumed tickborne illness. His condition deteriorated with respiratory and renal failure, lactic acidosis, and hypotension. Next-generation sequencing and phylogenetic analysis identified a reassortant Cache Valley virus.

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Cache Valley virus, Bunyamwera group viruses, Orthobunyavirus, next-generation sequencing, reassortant virus

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