Association between BRCA2 alterations and intraductal and cribriform histologies in prostate cancer

European Journal of Cancer（2021）

引用 42|浏览24

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摘要

•Presence of gBRCA2 mutations was not associated with IDC and CRIB patterns.•Results do not support germline BRCA2 testing only based on presence of IDC and/or CRIB.•IDC and CRIB patterns were associated with bi-allelic BRCA2 alterations in our study.

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关键词

Prostate cancer,BRCA2,Intraductal,Cribriform,Germline testing

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