Efficient C3-Alkylsulfenylation Of Indoles Under Mild Conditions Using Lewis Acid-Activated 8-Quinolinethiosulfonates

TETRAHEDRON LETTERS（2021）

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摘要

The activation of 8-quinolinethiosulfonates by zinc chloride promotes the usually difficult to achieve C3-alkylsulfenylation of indoles at room temperature under aerobic conditions. This strategy is compatible with substrates containing various functional groups. (C) 2021 Elsevier Ltd. All rights reserved.

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关键词

Sulfenylation, Thiosulfonate, Indole, Lewis acid, C-S bond

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