Chinese ovarian clear cell carcinoma cell line

The invention belongs to the field of microbial animal cell lines, and relates to a Chinese ovarian clear cell cancer cell line and an establishing method thereof. The Chinese ovarian clear cell cancer cell line is established by primordial culture of an in-vitro sample of an ovarian clear cell carcinoma patient, the Chinese ovarian clear cell cancer cell line is named as FDOV1, the deposit numberis NO. 13812, biological characteristics of the Chinese ovarian clear cell cancer cell line are as follows: the Chinese ovarian clear cell cancer cell line grows by adhering to a wall in a single layer manner, loses contact inhibition, has different shapes, and is round, oval, spindle-shaped, flat-shaped, or in irregular shape; grows well when in culture in vitro, and can continuously stably passto more than 50 generations; karyotype analysis results are similar to that of a diploid cell line, and show complex translocations, deletions and other chromosomal aberrations; exome sequencing shows that both ARID1A fs mutation and PIK3CA H1047R mutation are detected in the FDOV1 and clinical tumor tissues; the Chinese ovarian clear cell cancer cell line has good tumorigenicity, and can be usedto establish an animal model of ovarian clear cell carcinoma. The FDOV1 cell line can be used for studies of the pathogenesis, progression, and metastasis mechanism of the ovarian clear cell carcinoma, screening of new drugs, drug resistance mechanism and preclinical studies.