Extent of radiological response does not reflect survival in primary central nervous system lymphoma.

Matthijs van der Meulen,Alida A Postma,Marion Smits,Katerina Bakunina,Monique C Minnema,Tatjana Seute,Gavin Cull,Roelien H Enting,Marjolein van der Poel,Wendy B C Stevens,Dieta Brandsma,Aart Beeker,Jeanette K Doorduijn,Samar Issa,Martin J van den Bent,Jacoline E C Bromberg

Neuro-oncology advances（2021）

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摘要

Reliability of response assessment (CR/CRu/PR) is moderate even by central radiology review and these response categories do not reliably predict survival. Therefore, primary outcome in PCNSL studies should be survival rather than CR or CR/CRu-rate.

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关键词

MRI,central radiology review,complete response,response evaluation,survival

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