Gene expression patterns associated with tumor-infiltrating CD4+ and CD8+ T cells in invasive breast carcinomas

Human Immunology(2021)

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摘要
•In total, 478 and 796 genes were differentially expressed with a high vs. low stromal score and a high vs. low immune score, respectively.•MUC2 might be a biomarker to predict the prognosis of breast carcinoma.•The chr22-38_28785274-29006793.1–miR-34a/c-5p–CAPN6 axis might regulate cellular activities associated with CD4+ T cell infiltration in breast carcinoma.•The chr22-38_28785274-29006793.1–miR-494-3p–SLC9A7 axis might regulate cellular activities associated with CD8+ T cell infiltration in breast carcinoma.
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关键词
Invasive breast carcinomas,CD4+ T cells,CD8+ T cells,Competing endogenous RNAs
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