Metabolism of testosterone during weight loss in men with obesity

Frederique Van de Velde,Koen Deventer,Wim Van Gansbeke,Peter Van Eenoo,Pieter Van Renterghem,Tom Fiers,Tim Reyns,Jean Marc Kaufman,Yves Van Nieuwenhove,Bruno Lapauw

The Journal of Steroid Biochemistry and Molecular Biology（2021）

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摘要

•Three weeks after bariatric surgery SHBG and testosterone serum levels increase.•Decreased aromatization contributes to restoration of sex steroid profile.•Decreased metabolism of testosterone by the 5alpha-reductase pathway.•Increased production of testosterone is possible after bariatric surgery.

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关键词

Obesity,Testosterone,Metabolism,Weight loss,24h Urine

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