Formulation and stability of an extemporaneously compounded propafenone hydrochloride oral suspension for children with arrhythmia.

European journal of hospital pharmacy : science and practice(2022)

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摘要
Propafenone hydrochloride in a 10 mg/mL oral suspension prepared by diluting fine powder with a 1:1 mixture of Ora-Plus and Ora-Sweet and stored in high-density polyethylene bottles and has a beyond-use date of 90 days when stored at 2-8℃ or room temperature. This finding enables us to improve the accuracy of dosage administration and reduce the risk of medication errors affecting the paediatric population.
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关键词
cardiology,drug compounding,health services administration,paediatrics,pharmaceutical preparations,safety
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