Verification of CRISPR editing and finding transgenic inserts by Xdrop indirect sequence capture followed by short- and long-read sequencing

•Xdrop enrichment enables identification of unintended CRISPR edits.•Indirect sequence capture with Xdrop can enrich unknown regions.•Sequence coverage for >100 kilobases DNA only requires the design of a single standard primer set.•Xdrop enrichment is compatible with both long- and short-read sequencing.