Maternal platelets pass interstices of trophoblast columns and are not activated by HLA-G in early human pregnancy

Jacqueline Guettler,Désirée Forstner,Gerhard Cvirn,Sabine Maninger,Beatrice A Brugger,Olivia Nonn,Nadja Kupper,Elisabeth Pritz,Stefan Wernitznig,Gottfried Dohr,Heinz Hutter,Herbert Juch,Berend Isermann,Shrey Kohli,Martin Gauster

Journal of Reproductive Immunology（2021）

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摘要

•Platelets can be detected in interstices of extravillous trophoblasts columns.•Platelets are not activated by extravillous trophoblast marker HLA-G.•Platelet-derived factors could contribute to differentiation of invasive trophoblasts.

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CCL5,CXCL4,CLDN,Col-I,Col-IV,eNOS,EMT,EGF,FFPE,GA,hCG,HLA-G,ILT,MPP5,NO,OCLN,OCS,PAI,PRP,rHLA-G,RT,TF,TFPI,TGF-β,VWF,ZO-1

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