Serum metabolomic analysis of the anti-diabetic effect of Ginseng berry in type II diabetic rats based on ultra high-performance liquid chromatography-high resolution mass spectrometry

Heyu Wang,Rensong Huang,Hui Li,Lili Jiao,Shuying Liu,Wei Wu

Journal of Pharmaceutical and Biomedical Analysis（2021）

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摘要

•UHPLC-MS metabolomics was applied to study Ginseng berry treated T2DM.•Differential metabolites were identified by LC–MS/MS analysis.•Results verified the anti-diabetic and anti-oxidation effects of ginseng berry.•Ginseng berry treated T2DM by regulating multiple metabolic pathways.

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关键词

Ginseng berry,Ginsenoside,Type II diabetes mellitus,Metabolomics,UHPLC-Q-Exactive Orbitrap/MS

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