Heart Rate Variability during Wakefulness as a Marker of Obstructive Sleep Apnea Severity.

Hua Qin,Brendan T Keenan,Diego R Mazzotti,Fernando Vaquerizo-Villar,Jan F Kraemer,Niels Wessel,Sergio Tufik,Lia Bittencourt,Peter A Cistulli,Philip de Chazal,Kate Sutherland,Bhajan Singh,Allan I Pack,Ning-Hung Chen,Ingo Fietze,Thorarinn Gislason,Steven Holfinger,Ulysses J Magalang,Thomas Penzel

JOURNAL OF SLEEP RESEARCH（2021）

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摘要

Time-domain and non-linear HRV measures during wakefulness were associated with OSA severity, with severe patients having remarkably reduced and less complex HRV. Frequency-domain measures show a shift to sympathetic dominance only in obese OSA patients. Thus, HRV during wakefulness could provide additional information about cardiovascular physiology in OSA patients.

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关键词

autonomic nervous activity,frequency domain analysis,heart rate variability,nonlinear dynamic analysis,obstructive sleep apnea,time domain analysis,wakefulness

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