Weight Loss and Weight Regain in Usual Clinical Practice: Results From the TARGET-NASH Observational Cohort

Miguel H Malespin,Alfred Sidney Barritt,Stephanie E Watkins,Cheryl Schoen,Monica A Tincopa,Karen D Corbin,Andrea R Mospan,Breda Munoz,Huy N Trinh,L Michael Weiss,K Rajender Reddy,Rohit Loomba,Nyingi Kemmer,Anna S Lok

Clinical Gastroenterology and Hepatology（2022）

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摘要

First-line treatment for nonalcoholic fatty liver disease (NAFLD) focuses on weight loss through lifestyle modifications. Weight loss ≥5% results in reduction of steatosis and weight loss ≥10% has been associated with improvement in hepatic inflammation and fibrosis. The incidence and sustainability of weight loss among patients with NAFLD were estimated and associating factors identified.

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关键词

NAFLD,lifestyle modifications,obesity,real world

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