Fourier ptychographic rapid superresolution imaging via line-scanning microscopy with virtual structural- modulated

•We proposed a new method that combines virtual structural-modulated (VSM), line-scanning microscopy (LSM) and the Fourier ptychography (FP) algorithm to rapid super-resolution imaging.•The FP algorithm is fully compatible with vLSM, it may provide a turnkey solution for imaging biological samples with 2 times lateral resolution of wide-field and improved SNR and imaging speed.•We use the spatial frequency and phase modulation method in the cosine function, which avoids the problems of information loss and low SNR caused by the original FP recovery algorithm.