A cynomolgus monkey with naturally occurring Parkinson's disease

Evidence for the existence of mon-keys with spontaneous Parkinson's disease(PD)has been lacking.Here,we screened macaque colonies at the Kunming Primate Research Center(Association for Assessment and Ac-creditation of Laboratory Animal Care(AAALAC)accredited),Kunming In-stitute of Zoology,Chinese Academy of Sciences,which has a large population of monkeys(＞2400),to identify naturally occurring PD monkeys.Sixty cynomol-gus macaques and rhesus macaques with no experimental experience,housed in single cages of the Kunming Primate Research Center,were selected as the subjects of a preliminary screen proce-dure to search for naturally occurring PD(Supplementary Fig.S1).The subjects'age,gender and species information are listed in Supplementary Table S1.