SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES (SPION) APPLICATIONS IN CANCER

The development of superparamagnetic iron oxide nanoparticles (SPION) for diagnosis and therapy (the-ranostics) in cancer has marked important progress over the last two decades. SPION has been developed as an imagistic contrast agent, a vehicle for targeted delivery and most recently as an initiator in cancer cell death using magnetic and photonic ablation. Properties like biocompatibility, superparamagnetism and biodegradability promote their usage in cancer research. This paper revolves around SPION applications in cancer diagnostic and therapy.