Generation of antimicrobial peptides Leg1 and Leg2 from chickpea storage protein, active against food spoilage bacteria and foodborne pathogens
Food Chemistry(2021)
摘要
•Virtual screening identified 21 antimicrobial peptide candidates from chickpea.•Leg1 and Leg2 exhibit strong bacteriostatic and bactericidal activity.•Both were active against 16 pathogens, antibiotic-resistant and spoilage bacteria.•10–1,000 fold higher activity compared to conventional preservatives.•Atomistic MD simulation indicates specific interaction with the bacterial membrane.
更多查看译文
关键词
AMP,LC–ESI–QTOF-MS/MS,UHPLC,OD,MIC,MBC,MD,DMPE,DMPC,PMF,COM
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要