Ultrasound combined with microbubbles enhances the renoprotective effects of methylprednisolone in rats with adriamycin-induced nephropathy

Shuting Ren,Ruoyan Si,Pengfei Sun,Tieqiao Wu,Aozhi Dai,Lina Chen,Wenbao Zhao,Tuo Han, Xin Zhang,Zhonglin Chai

European Journal of Pharmaceutical Sciences（2021）

引用 4|浏览8

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摘要

•40 mg/kg methylprednisolone ameliorated renal injury in rats with nephropathy.•Ultrasound combined with microbubbles enhance methylprednisolone's renoprotection.•Ultrasound combined with microbubbles reduce methylprednisolone dosage used.

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关键词

Drug delivery,Methylprednisolone,Microbubble,Nephropathy,Proteinuria,Ultrasound

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