Bnct For Primary Synovial Sarcoma

APPLIED RADIATION AND ISOTOPES(2021)

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摘要
Synovial sarcoma is a rare tumor requiring new treatment methods. A 46-year-old woman with primary monophasic synovial sarcoma in the left thigh involving the sciatic nerve, declining surgery because of potential dysfunction of the affected limbs, received two courses of BNCT. The tumor thus reduced was completely resected with no subsequent recurrence. The patient is now able to walk unassisted, and no local recurrence has been observed, demonstrating the applicability of BNCT as adjuvant therapy for synovial sarcoma. Further study and analysis with more experience accumulation are needed to confirm the real impact of BNCT efficacy for its application to synovial sarcoma.
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关键词
Boron neutron capture therapy (BNCT), p-borono-L-phenylalanine (BPA), 4-borono-2-F-18-fluoro-L-phenylalanine positron emission tomography/computed tomography, F-18-fluorodeoxyglucose positron emission tomography/computed tomography, L-type amino acid transporter 1, Ki-67, Primary, Synovial sarcoma, Clinical treatment, Monophasic subtype, Biphasic subtype, Adjuvant therapy
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