Differential response to SSRI versus Placebo and distinct neural signatures among data-driven subgroups of patients with major depressive disorder

Journal of Affective Disorders(2021)

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摘要
•Four principal components identified from 27 clinical measures•Groups differed based on childhood trauma, hypomania, agreeableness and openness•Subgroups who respond differently to SSRI vs. placebo have distinct neural signatures
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关键词
Data Driven,Clinical,Subgroups,SSRI,fMRI,Major Depressive Disorder
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