Is Adjunctive Hyperbaric Oxygen Treatment Alone or with Surgery the Proper Management for Active and Persistent Osteoradionecrosis?

Kamonwan Jenwitheesuk,Ajanee Mahakkanukrauh, Wiyada Punjaruk,Patravoot Vatanasapt, Kriangsak Jenwitheesuk,Palakorn Surakunprapha,Suthin Jinaporntham, Krittinant Uraiwan,Phasuk Limrattanapimpa

Advances in skin & wound care（2021）

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ABSTRACT:This study enrolled patients with stage 3 osteoradionecrosis. There were three treatment modalities: antibiotics, hyperbaric oxygen therapy (HBOT), and surgery. Complete healing was the primary outcome. Multiple logistic regression analysis demonstrated that surgery with HBOT improved wound healing better than HBOT alone.

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