Specific Norovirus Interaction with Lewis x and Lewis a on Human Intestinal Inflammatory Mucosa during Refractory Inflammatory Bowel Disease

Georges Tarris,Alexis de Rougemont,Marie Estienney,Maeva Charkaoui,Thomas Mouillot,Bernard Bonnotte,Christophe Michiels,Laurent Martin,Gaël Belliot, Michael J. Imperiale

MSPHERE（2021）

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摘要

Inflammatory bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), are progressive diseases affecting millions of people each year. Flare-ups during IBD result in severe mucosal alterations of the small intestine (in CD) and in the colon and rectum (in CD and UC).

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关键词

Crohn’s disease,ulcerative colitis,norovirus,HBGA,inflammation,gut inflammation

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