The nAChR Chaperone TMEM35a (NACHO) Contributes to the Development of Hyperalgesia in Mice

Sergey G. Khasabov,Victoria M. Rogness, Montana B. Beeson,Lucy Vulchanova,Li-Lian Yuan,Donald A. Simone,Phu V. Tran

Neuroscience（2021）

引用 4|浏览12

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摘要

•NACHO modulates spinal cord pain transmission.•Specific loss of neuronal α7 in tmem35a KO mice results in heat hyperalgesia.•The tmem35a KO spinal cord transcriptome indicates increased neuroinflammation.

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关键词

CGRP,IB4,IPA,NACHO,nAChR

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