Safety and efficacy of ozone therapy in mild to moderate COVID-19 patients: A phase 1/11 randomized control trial (SEOT study)

•Ozone therapy as an adjuvant care can shorten hospitalization and need for intensive care.•Ozone therapy enhances the quality of care in COVID-19 by exhibiting immune-modulatory effects.•Ozone therapy as an adjuvant therapy is safe and effective in COVID-19 care .•Ozone therapy relieves cardinal symptoms of SARS-CoV-2 like breathlessness, cough etc.