Rapid identification and detection of β-lactamase-producing Enterobacteriaceae from positive blood cultures by MALDI-TOF/MS

Greta Roncarati,Claudio Foschi,Simone Ambretti,Maria Carla Re

Journal of Global Antimicrobial Resistance（2021）

引用 12|浏览5

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摘要

•MALDI-TOF method is proposed for resistance detection from positive blood cultures.•Workflow is based on hydrolysis assays of cefotaxime and ertapenem.•Workflow showed high sensitivity and specificity, with reduced turnaround-time.•Particularly suitable where ESβL and class A carbapenemases are highly widespread.

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关键词

Blood cultures,MALDI-TOF/MS,Enterobacteriaceae,Hydrolysis assay,Rapid identification

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