Endothelial Cu Transporter Atp7a Promotes Vegfr2 Signaling And Post-Ischemic Neovascularization Via Regulating Autophagy

Dipankar Ash,Sudhahar Varadarajan,Seock-Won Youn,Mustafa N. Okur, John P. O'Brien, Malgorzata Mcmenamin, Xuexiu Fang,Yali Hou,Jack Kaplan,Tohru Fukai,Masuko Ushio-Fukai

Circulation（2020）

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摘要

Background: VEGFR2 (KDR/Flk1) signaling in endothelial cells (ECs) plays a central role in angiogenesis. Copper (Cu) is essential micronutrient and has been implicated in angiogenesis. The P-type A...

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