Abstract 13932: Lung-targeted Sin3a Gene Therapy as a Promising Strategy to Restore Bmpr2 Expression in Pulmonary Arterial Hypertension

Malik Bisserier,Prabhu Mathiyalagan,Yassine Abdeldjebbar,Shihong Zhang,Firas Elmastour,Peter Dorfmüller,Marc Humbert,Yassine Sassi,Thomas Weber,Frederic Perros,Susmita Sahoo,Lahouaria Hadri

Circulation（2020）

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Background: Pulmonary arterial hypertension (PAH) is a fatal lung disease of multifactorial etiology, with no curative treatment. Several studies have previously suggested that hypermethylation of ...

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