Lamin A Deficiency Leads To Electrophysiological And Nuclear Abnormalities Reminiscent Of Atrial Cardiomyopathy In Zebrafish

Ryota Teramoto,Kenshi Hayashi,Manu Beerens,David Chiang,Tuomas O. Kiviniemi,Masahiro Satoh, K. C. Ashmita,Micah Burch,Wandi Zhu,Wei Dai, Jing Liu,Aparna Mahadevan,Eva Buys,Calum Macrae

Circulation（2020）

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摘要

Introduction: Mutations in the lamin A/C (LMNA) gene have been causally linked to atrial arrhythmias and cardiac conduction disease (CCD) in young adults. However, the mechanism by which the lamino...

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